Description

α-D-Lactopyranose Heptaacetate Trichloroacetimidate is a high-purity, advanced glycosyl donor used in stereoselective glycosylation reactions. This compound is critical for the efficient and controlled synthesis of complex oligosaccharides and glycoconjugates. It is an essential building block for researchers and manufacturers in pharmaceutical development, particularly for creating novel carbohydrate-based drugs, vaccines, and diagnostic agents.

Application

• Glycochemistry Research: A key reagent for the synthesis of complex oligosaccharides and glycans with precise stereochemistry.
• Pharmaceutical Intermediates: Used in the production of carbohydrate-based active pharmaceutical ingredients (APIs) for antiviral, anticancer, and antibacterial therapies.
• Vaccine Development: Critical for constructing antigenic carbohydrate moieties in conjugate vaccine candidates.
• Glycobiology Studies: Enables the creation of defined glycan structures for studying protein-carbohydrate interactions and cell signaling.
• Diagnostic Reagents: Serves as a precursor for labeled glycans used in diagnostic assays and imaging probes.
• Process Development: Employed in scaling up glycosylation steps for commercial manufacturing of carbohydrate drugs.

Basic Information

Product Name	α-D-Lactopyranose Heptaacetate Trichloroacetimidate
CAS No.	106256-81-9
Molecular Formula	C23H26Cl3NO13
Molecular Weight	630.80 g/mol
Synonyms	1,2,3,4,6-Penta-O-acetyl-α-D-glucopyranosyl Trichloroacetimidate; α-D-Glucopyranose, 1,2,3,4,6-pentaacetate, 1-(2,2,2-trichloroethanimidate); Penta-O-acetyl-α-D-glucopyranosyl Trichloroacetimidate; α-Acetobromoglucose Trichloroacetimidate Derivative; Glc(Ac)5-α-Trichloroacetimidate; Glycosyl Donor for Koenigs-Knorr Type Reactions; α-D-Glucose Pentaacetate Trichloroacetimidate; TCAI-Glc(Ac)5
EINECS	Contact for details

Quality Control

Our α-D-Lactopyranose Heptaacetate Trichloroacetimidate is manufactured under strict quality systems to ensure batch-to-batch consistency for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.