Description

6-Fluoro-5'-Deoxypyridoxal is a strategically fluorinated derivative of the essential vitamin B6 cofactor, pyridoxal. This modification enhances its metabolic stability and binding affinity, making it a critical building block for advanced biochemical research and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the life sciences sector for probing enzyme mechanisms and developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly enzyme inhibitors targeting vitamin B6-dependent pathways.
• Biochemical Research: Used as a stable, fluorinated analog to study the structure, function, and catalytic mechanisms of pyridoxal phosphate (PLP)-dependent enzymes.
• Probe Development: Acts as a core structure for creating fluorescent or affinity probes to label and isolate specific enzymes in complex biological systems.
• Metabolite Analysis: Employed as a reference standard in analytical methods (HPLC, LC-MS) for quantifying vitamin B6 metabolites and related compounds in research samples.

Basic Information

Product Name	6-Fluoro-5'-Deoxypyridoxal
CAS No.	106212-90-2
Molecular Formula	C₈H₈FNO₃
Molecular Weight	185.15 g/mol
Synonyms	5'-Deoxy-6-fluoropyridoxal; 6-Fluoro-5'-deoxy-Pyridoxal; 3-Hydroxy-5-(hydroxymethyl)-2-methyl-4-fluoropyridine-4-carboxaldehyde; 4-Pyridinecarboxaldehyde, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-fluoro-; Fluorodeoxypyridoxal
EINECS	Contact for details

Quality Control

Every batch of 6-Fluoro-5'-Deoxypyridoxal is manufactured and analyzed under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your research and development needs. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic results are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and hygroscopic (moisture-sensitive); handle under an inert atmosphere if prolonged exposure is anticipated.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.