Description

L-Proline, 5-Oxo-, Dihydroxymethylsilyl Ester is a specialized organosilicon derivative of a proline precursor, offering unique reactivity and stability for advanced synthetic applications. This compound is valued for its role as a versatile building block in the development of novel silicon-containing molecules and functional materials. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and material science sectors for creating innovative compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for introducing silicon into bioactive molecules.
• Agrochemical Synthesis: Used in the development of new generation pesticides and herbicides, where the silicon moiety can enhance stability or bioavailability.
• Material Science Research: Acts as a precursor for silicon-based polymers, coatings, or hybrid organic-inorganic materials (ORMOSILs) with specific mechanical or optical properties.
• Cross-Coupling Reactions: Functions as a reagent in palladium-catalyzed and other metal-mediated coupling reactions to construct complex molecular architectures.
• Asymmetric Catalysis Ligand Precursor: Potential use in the synthesis of chiral ligands or catalysts for enantioselective transformations.
• Surface Modification Agent: Can be utilized to modify the surface properties of silica or other materials for specialized applications.

Basic Information

Product Name	L-Proline, 5-Oxo-, Dihydroxymethylsilyl Ester
CAS No.	105883-41-8
Molecular Formula	C9H17NO5Si
Molecular Weight	247.32 g/mol
Synonyms	Dihydroxymethylsilyl 5-oxo-L-prolinate; (5-Oxo-L-prolinato-O)dihydroxymethylsilane; 5-Oxo-L-proline dihydroxymethylsilyl ester; Methylsilanediol 5-oxoproline ester; L-Pyroglutamic acid dihydroxymethylsilyl ester; Silicon-modified L-pyroglutamate
EINECS	Contact for details

Quality Control

Our L-Proline, 5-Oxo-, Dihydroxymethylsilyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.