Description

1-(4-Fluorophenyl)-3-(3,4,5-Trimethoxyphenyl)Prop-2-En-1-One is a high-purity synthetic chalcone derivative, a key structural motif in medicinal chemistry. This compound matters as a versatile and valuable pharmaceutical intermediate for research and development, offering a precise chemical scaffold for creating novel bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for synthesizing potential drug candidates and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in oncology, anti-inflammatory, and CNS therapeutic areas.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis due to its chalcone structure.
• Agrochemical Development: Used in research for creating new active ingredients for crop protection products.
• Chemical Biology Probes: Acts as a starting material for developing molecular probes to study biological pathways and protein functions.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to create complex, high-value specialty chemicals.
• Academic & Institutional R&D: Utilized in universities and research institutes for fundamental chemical research and discovery projects.

Basic Information

Product Name	1-(4-Fluorophenyl)-3-(3,4,5-Trimethoxyphenyl)Prop-2-En-1-One
CAS No.	105686-90-6
Molecular Formula	C18H17FO4
Molecular Weight	316.33 g/mol
Synonyms	3-(3,4,5-Trimethoxyphenyl)-1-(4-fluorophenyl)-2-propen-1-one; (E)-1-(4-Fluorophenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one; 4-Fluoro-3',4',5'-trimethoxychalcone; 3,4,5-Trimethoxy-4'-fluorochalcone; 4'-Fluoro-3,4,5-trimethoxychalcone; Chalcone derivative 105686-90-6; FMC
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorophenyl)-3-(3,4,5-Trimethoxyphenyl)Prop-2-En-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) with full specification data are provided to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.