Description

2-Amino-1-Methyl-6-Phenylimidazo[4,5-B]Pyridine is a heterocyclic aromatic amine of significant interest in advanced chemical research and development. This compound serves as a critical building block and reference standard in the study of mutagenic and carcinogenic substances. It is primarily utilized by research institutions and industrial laboratories focused on analytical chemistry, toxicology, and food safety. The compound, with CAS number 105650-23-5, is essential for method development, calibration, and quality control in these specialized fields.

Application

• Analytical Reference Standard: Used as a certified standard for the quantification of heterocyclic aromatic amines (HAAs) in complex matrices.
• Food Safety Research: Critical for studying the formation and mitigation of mutagenic compounds in cooked protein-rich foods.
• Toxicology & Metabolic Studies: Employed in in vitro and in vivo research to understand the metabolic activation, DNA adduct formation, and carcinogenic potential of HAAs.
• Method Development & Validation: Serves as a key analyte for developing and validating sensitive analytical methods such as LC-MS/MS, GC-MS, and HPLC.
• Biomarker Research: Used in studies investigating HAA exposure biomarkers in biological fluids.
• Pharmaceutical Impurity Profiling: Acts as a model compound or potential impurity standard in relevant pharmaceutical research.

Basic Information

Product Name	2-Amino-1-Methyl-6-Phenylimidazo[4,5-B]Pyridine
CAS No.	105650-23-5
Molecular Formula	C13H12N4
Molecular Weight	224.26 g/mol
Synonyms	PhIP; 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine; 1-Methyl-6-phenyl-2-aminoimidazo[4,5-b]pyridine; 2-Amino-1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridine; 2-Amino-1-methyl-6-phenylimidazopyridine; Imidazo[4,5-b]pyridin-2-amine, 1-methyl-6-phenyl-; HAA PhIP; CAS 105650-23-5
EINECS	Contact for details

Quality Control

Our 2-Amino-1-Methyl-6-Phenylimidazo[4,5-B]Pyridine is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant guidelines for reference standard materials, ensuring data integrity for your critical research and analytical work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and opened under minimum light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.