Description

Methyl 1,2,3,4-Tetrahydro-2-Oxoquinoline-3-Carboxylate is a high-value heterocyclic building block and synthetic intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a versatile precursor in the development of complex pharmacologically active molecules, enabling the construction of intricate quinoline-based scaffolds. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process R&D, and the synthesis of novel compounds for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Medicinal Chemistry Research: Used in the exploration of structure-activity relationships (SAR) and the development of novel quinoline and tetrahydroquinoline derivatives with optimized biological profiles.
• Process Chemistry Development: Serves as a critical starting material or intermediate in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Potential intermediate in the research and development of new agrochemicals, such as herbicides or fungicides, leveraging the bioactive quinoline core.
• Academic & Industrial R&D: Employed in organic synthesis laboratories for methodological studies, heterocyclic chemistry research, and the creation of specialized chemical libraries.

Basic Information

Product Name	Methyl 1,2,3,4-Tetrahydro-2-Oxoquinoline-3-Carboxylate
CAS No.	105404-33-9
Molecular Formula	C11H11NO3
Molecular Weight	205.21 g/mol
Synonyms	Methyl 2-oxo-1,2,3,4-tetrahydroquinoline-3-carboxylate; 3-Quinolinecarboxylic acid, 1,2,3,4-tetrahydro-2-oxo-, methyl ester; Methyl 1,2,3,4-tetrahydro-2-oxo-3-quinolinecarboxylate; 3-Carbomethoxy-1,2,3,4-tetrahydro-2-quinolone; 3-Methoxycarbonyl-1,2,3,4-tetrahydro-2-quinolone; 2-Oxo-1,2,3,4-tetrahydroquinoline-3-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 1,2,3,4-Tetrahydro-2-Oxoquinoline-3-Carboxylate is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research or development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.