Description

1(3H)-Isobenzofuranone, 5-Fluoro-3-Hydroxy- is a high-purity fluorinated isobenzofuranone derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique molecular scaffold, which incorporates both fluorine and hydroxyl functional groups, enabling precise structural modifications in complex molecule synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides, where the fluorine atom enhances biological activity and stability.
• Material Science Research: Serves as a monomer or precursor for specialty polymers and advanced organic electronic materials.
• Organic Synthesis: A versatile reagent for constructing complex heterocyclic compounds and fused ring systems in academic and industrial R&D.
• Fluorine Chemistry Studies: Valuable substrate for investigating novel fluorination reactions and studying structure-activity relationships (SAR).

Basic Information

Product Name	1(3H)-Isobenzofuranone, 5-Fluoro-3-Hydroxy-
CAS No.	105398-57-0
Molecular Formula	C8H5FO3
Molecular Weight	168.12 g/mol
Synonyms	5-Fluoro-3-hydroxyphthalide; 3-Hydroxy-5-fluorophthalide; 5-Fluoro-3-hydroxy-1(3H)-isobenzofuranone; 5-Fluoro-3-hydroxylphthalide; 3-Hydroxy-5-fluoro-1(3H)-isobenzofuranone; 5-Fluoro-3-hydroxy-2-benzofuran-1(3H)-one
EINECS	Contact for details

Quality Control

Our 1(3H)-Isobenzofuranone, 5-Fluoro-3-Hydroxy- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) with complete batch data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.