Description

(6R)-(-)-4,10-Dimethyl-7-Isopropyl-1,5-Dioxaspiro[5.5]Undec-3-En-2-On is a high-purity, chiral spirocyclic compound that serves as a critical advanced intermediate in organic synthesis. Its unique stereochemistry and complex molecular architecture make it invaluable for constructing sophisticated target molecules with precise spatial orientation. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fragrances.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory agents.
• Agrochemical Research: Used in the development of novel, stereospecific pesticides and herbicides where the specific enantiomeric form can significantly influence biological activity and environmental safety.
• Flavor & Fragrance (F&F) Industry: Serves as a precursor for high-value aroma chemicals and musk analogs, contributing unique olfactory properties to premium fragrance formulations.
• Academic & R&D Laboratories: Employed as a model compound or starting material in methodological studies for asymmetric synthesis, catalysis, and the development of new spirocyclization techniques.
• Material Science: Potential monomer or additive for creating specialized polymers with tailored optical or structural properties.

Basic Information

Product Name	(6R)-(-)-4,10-Dimethyl-7-Isopropyl-1,5-Dioxaspiro[5.5]Undec-3-En-2-On
CAS No.	105367-62-2
Molecular Formula	C15H22O3
Molecular Weight	250.33 g/mol
Synonyms	(6R)-4,10-Dimethyl-7-(propan-2-yl)-1,5-dioxaspiro[5.5]undec-3-en-2-one; (-)-4,10-Dimethyl-7-isopropyl-1,5-dioxaspiro[5.5]undec-3-en-2-one; (6R)-(-)-Spirocyclic Enone Derivative; 1,5-Dioxaspiro[5.5]undec-3-en-2-one, 4,10-dimethyl-7-(1-methylethyl)-, (6R)-; (6R)-4,10-Dimethyl-7-isopropyl-1,5-dioxaspiro[5.5]undec-3-en-2-one
EINECS	Contact for details

Quality Control

Our production of (6R)-(-)-4,10-Dimethyl-7-Isopropyl-1,5-Dioxaspiro[5.5]Undec-3-En-2-On adheres to stringent quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is subjected to comprehensive analytical testing, including chiral HPLC, NMR, and GC-MS, to verify identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP-compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be sensitive to prolonged exposure to air and moisture; therefore, it is recommended to store under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.