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Benzyl (2S,3R)-(+)-6-Oxo-2,3-Diphenyl-4-Morpholinecarboxylate CAS NO 105228-46-4


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CAS No.:105228-46-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Benzyl (2S,3R)-(+)-6-Oxo-2,3-Diphenyl-4-Morpholinecarboxylate is a high-purity chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry makes it a critical reagent for the preparation of enantiomerically pure compounds, particularly in pharmaceutical research and development. This compound is essential for chemists and manufacturers in the fine chemical, agrochemical, and active pharmaceutical ingredient (API) sectors who require reliable, high-quality intermediates for complex asymmetric syntheses.

Application

  • Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
  • Asymmetric Catalyst Ligand Precursor: Used in the development and preparation of chiral ligands for transition metal catalysis.
  • Agrochemical Synthesis: Serves as a building block for creating enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
  • Academic & Industrial Research: A valuable tool for methodological development in stereoselective synthesis and total synthesis of natural products.
  • Fine Chemical Production: Employed in the manufacture of specialty chemicals where control of absolute stereochemistry is paramount.

Basic Information

Product Name Benzyl (2S,3R)-(+)-6-Oxo-2,3-Diphenyl-4-Morpholinecarboxylate
CAS No. 105228-46-4
Molecular Formula C24H21NO4
Molecular Weight 387.43 g/mol
Synonyms (2S,3R)-Benzyl 6-oxo-2,3-diphenylmorpholine-4-carboxylate; (+)-Benzyl 2,3-diphenyl-6-oxomorpholine-4-carboxylate; Benzyl (2S,3R)-2,3-diphenyl-6-oxo-1,4-oxazinane-4-carboxylate; 4-Morpholinecarboxylic acid, 6-oxo-2,3-diphenyl-, phenylmethyl ester, (2S,3R)-; (2S,3R)-Benzyl 2,3-diphenyl-1,4-oxazin-6-one-4-carboxylate; Chiral morpholine-4-carboxylate ester; BDP-Morpholine carboxylate benzyl ester
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Quality Control

Our Benzyl (2S,3R)-(+)-6-Oxo-2,3-Diphenyl-4-Morpholinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and identity confirmation by spectroscopic methods, to ensure it meets the high standards required for research and cGMP manufacturing. Certificates of Analysis (COA) detailing purity, chiral excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Assay (HPLC) ≥ 98.0%
Chiral Purity (Chiral HPLC) ≥ 99.0% e.e.
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Single Unknown Impurity (HPLC) ≤ 0.5%
Total Impurities (HPLC) ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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