Description

3-Acetyl-n-[(Phenylmethoxy)Carbonyl]-o-(Phenylmethyl)-L-Tyrosine Methyl Ester is a sophisticated, protected tyrosine derivative that serves as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates for the development of complex peptides and other bioactive molecules. It is primarily utilized in pharmaceutical R&D and fine chemical production, where precise molecular architecture is paramount for creating novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Chemistry Research: Used in solid-phase and solution-phase peptide synthesis (SPPS) to introduce protected tyrosine residues into peptide chains.
• Proteomics & Biochemistry: Serves as a specialized reagent for studying protein structure-function relationships and enzyme-substrate interactions.
• Fine Chemical Synthesis: Employed in the construction of non-natural amino acid derivatives and other structurally complex organic molecules.
• Academic & Industrial R&D: A valuable tool for medicinal chemists and research scientists exploring new chemical entities in drug discovery programs.

Basic Information

Product Name	3-Acetyl-n-[(Phenylmethoxy)Carbonyl]-o-(Phenylmethyl)-L-Tyrosine Methyl Ester
CAS No.	105205-69-4
Molecular Formula	C28H27NO7
Molecular Weight	489.52 g/mol
Synonyms	N-[(Benzyloxy)carbonyl]-O-benzyl-N-acetyl-L-tyrosine methyl ester; Z-O-Bzl-N-Ac-Tyr-OMe; N-Cbz-O-Benzyl-N-acetyl-L-tyrosine methyl ester; Methyl Nα-acetyl-Nε-[(benzyloxy)carbonyl]-O-benzyl-L-tyrosinate; N-Acetyl-N-Cbz-O-benzyl-L-tyrosine methyl ester; Fmoc-Tyr(Bzl)-OH (Note: This is a related, but different, protected tyrosine); L-Tyrosine, N-acetyl-N-[(phenylmethoxy)carbonyl]-O-(phenylmethyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our 3-Acetyl-n-[(Phenylmethoxy)Carbonyl]-o-(Phenylmethyl)-L-Tyrosine Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for research and synthesis. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.