Description

α-[[(2α,3α)-2,3-Dimethyl-1-Aziridinyl]Methyl]-2-Nitro-1H-Imidazole-1-Ethanol is a specialized nitroimidazole derivative with a functionalized aziridine moiety, representing a high-value synthetic intermediate in advanced organic synthesis. Its molecular architecture is critical for the development of targeted bioactive compounds, particularly in pharmaceutical research. This compound is essential for R&D chemists and process development scientists working in medicinal chemistry, agrochemical discovery, and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel nitroimidazole-based drug candidates, including potential antimicrobial and antiparasitic agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its reactive aziridine group.
• Bioconjugation & Probe Development: Serves as a precursor for creating chemical probes and affinity labels for biological target identification.
• Agrochemical Synthesis: Intermediate in the development of new crop protection agents and herbicides.
• Academic & Institutional R&D: Employed in universities and research institutes for investigating new heterocyclic reaction methodologies.
• Fine Chemical Production: Used in custom synthesis and contract manufacturing of complex, high-purity specialty chemicals.

Basic Information

Product Name	α-[[(2α,3α)-2,3-Dimethyl-1-Aziridinyl]Methyl]-2-Nitro-1H-Imidazole-1-Ethanol
CAS No.	105027-77-8
Molecular Formula	C₁₀H₁₆N₄O₃
Molecular Weight	240.26 g/mol
Synonyms	1-(2,3-Dimethylaziridin-1-yl)-3-(2-nitro-1H-imidazol-1-yl)propan-2-ol; 2-Nitro-1-[2-[(2,3-dimethylaziridin-1-yl)methyl]-2-hydroxyethyl]-1H-imidazole; α-[[(2α,3α)-2,3-Dimethyl-1-aziridinyl]methyl]-2-nitro-1H-imidazole-1-ethanol; (αR)-α-[[(2α,3α)-2,3-Dimethyl-1-aziridinyl]methyl]-2-nitro-1H-imidazole-1-ethanol; Nitroimidazole-aziridine hybrid; Aziridinylmethyl nitroimidazole ethanol derivative
EINECS	Contact for details

Quality Control

Our α-[[(2α,3α)-2,3-Dimethyl-1-Aziridinyl]Methyl]-2-Nitro-1H-Imidazole-1-Ethanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.