Description

1-(2-(4-Azidophenyl)Ethyl)-4-(3-Trifluoromethylphenyl)Piperazine is a specialized organic compound featuring a unique piperazine core functionalized with both an azidophenyl and a trifluoromethylphenyl group. This molecular architecture makes it a valuable building block and intermediate in advanced chemical synthesis, particularly for applications requiring photolabile or click chemistry handles. It is primarily needed by pharmaceutical researchers, agrochemical developers, and material scientists engaged in the discovery and development of novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in developing novel herbicides, fungicides, or insecticides that leverage the trifluoromethyl group for enhanced bioactivity and stability.
• Photoaffinity Labeling Probes: The azide group allows this compound to be used in creating probes for studying protein-ligand interactions and biological pathways.
• Click Chemistry: Serves as a critical component in Huisgen 1,3-dipolar cycloaddition reactions for bioconjugation and polymer functionalization.
• Material Science: Intermediate for synthesizing advanced polymers and coatings with specific surface properties or light-responsive behavior.
• Chemical Biology Tool Development: Building block for creating molecular tools used to investigate cellular processes and enzyme functions.

Basic Information

Product Name	1-(2-(4-Azidophenyl)Ethyl)-4-(3-Trifluoromethylphenyl)Piperazine
CAS No.	105025-90-9
Molecular Formula	C19H20F3N5
Molecular Weight	375.39 g/mol
Synonyms	4-[2-[4-(3-Trifluoromethylphenyl)piperazin-1-yl]ethyl]phenyl azide; 1-[2-(4-Azidophenyl)ethyl]-4-(3-trifluoromethylphenyl)piperazine; N-(4-Azidophenethyl)-4-(3-(trifluoromethyl)phenyl)piperazine; 105025-90-9; 4-(3-Trifluoromethylphenyl)-1-[2-(4-azidophenyl)ethyl]piperazine
EINECS	Contact for details

Quality Control

Our 1-(2-(4-Azidophenyl)Ethyl)-4-(3-Trifluoromethylphenyl)Piperazine is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic and light-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.