Description

Bicyclo[2.1.0]Pentane-2-Carboxylic Acid, Methyl Ester, (1-α-,2-α-,4-α-)- (9Ci) is a high-purity, strained bicyclic organic ester of significant interest in advanced synthetic chemistry. This compound serves as a critical chiral building block and specialty intermediate for the development of novel molecular architectures. It is primarily utilized by research institutions and industrial R&D departments focused on pharmaceutical discovery, agrochemical synthesis, and materials science, where its unique three-dimensional structure enables the exploration of new chemical space.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting complex molecular scaffolds.
• Agrochemical Synthesis: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its strained ring system to impart specific biological activity.
• Advanced Material Precursor: Serves as a monomer or building block for specialty polymers and functional materials requiring rigid, three-dimensional components.
• Organic Synthesis Reagent: Employed in academic and industrial research for cycloaddition reactions, ring-opening transformations, and as a template in stereoselective synthesis.
• Ligand and Catalyst Development: Utilized in the design and synthesis of novel chiral ligands and organocatalysts for asymmetric catalysis.
• Flavor and Fragrance Chemistry: Acts as an intermediate for synthesizing complex odorants and flavor compounds with unique sensory profiles.

Basic Information

Product Name	Bicyclo[2.1.0]Pentane-2-Carboxylic Acid, Methyl Ester, (1-α-,2-α-,4-α-)- (9Ci)
CAS No.	105017-03-6
Molecular Formula	C8H12O2
Molecular Weight	140.18 g/mol
Synonyms	Methyl bicyclo[2.1.0]pentane-2-carboxylate; (1α,2α,4α)-Bicyclo[2.1.0]pentane-2-carboxylic acid methyl ester; Methyl (1R,2S,4R)-bicyclo[2.1.0]pentane-2-carboxylate; Methyl 2-bicyclo[2.1.0]pentanecarboxylate; Bicyclo[2.1.0]pentane-2-carboxylic acid methyl ester, (1α,2α,4α)-; 105017-03-6; Methyl (1α,2α,4α)-bicyclo[2.1.0]pentane-2-carboxylate
EINECS	Contact for details

Quality Control

Our production of Bicyclo[2.1.0]Pentane-2-Carboxylic Acid, Methyl Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We employ advanced analytical techniques including GC, HPLC, NMR, and chiral analysis to verify specifications. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.