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6-Phenyl-4-(Trifluoromethyl)Thieno-[2,3-B]Pyridin-3-Amine CAS NO 104960-57-8


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CAS No.:104960-57-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-Phenyl-4-(Trifluoromethyl)Thieno-[2,3-B]Pyridin-3-Amine is a high-value, multi-functional heterocyclic building block characterized by its fused thienopyridine core and trifluoromethyl group. This compound is essential for advanced research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by pharmaceutical R&D teams, agrochemical innovators, and specialty chemical manufacturers for creating compounds with enhanced biological activity and metabolic stability.

Application

  • Pharmaceutical Intermediate: A key synthon for developing novel drug candidates, especially in therapeutic areas like oncology, CNS disorders, and anti-infectives.
  • Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the thienopyridine scaffold.
  • Material Science Precursor: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
  • Chemical Biology Probe: Utilized in medicinal chemistry to study protein-ligand interactions and enzyme inhibition mechanisms.
  • Custom Synthesis & Contract Manufacturing: A critical starting material for CDMOs (Contract Development and Manufacturing Organizations) offering bespoke chemical synthesis services.

Basic Information

Product Name 6-Phenyl-4-(Trifluoromethyl)Thieno-[2,3-B]Pyridin-3-Amine
CAS No. 104960-57-8
Molecular Formula C15H9F3N2S
Molecular Weight 306.31 g/mol
Synonyms 3-Amino-6-phenyl-4-(trifluoromethyl)thieno[2,3-b]pyridine; 6-Phenyl-4-(trifluoromethyl)thieno[2,3-b]pyridin-3-amine; Thieno[2,3-b]pyridin-3-amine, 6-phenyl-4-(trifluoromethyl)-; 104960-57-8; 6-Phenyl-4-trifluoromethylthieno[2,3-b]pyridin-3-ylamine
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Quality Control

Our 6-Phenyl-4-(Trifluoromethyl)Thieno-[2,3-B]Pyridin-3-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item Specification
Appearance Off-white to light yellow crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference standard
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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