Description

2-Mercapto-6-Thien-2-Yl-4-(Trifluoromethyl)-Pyridine-3-Carbonitrile is a high-value, multi-functional heterocyclic building block characterized by its pyridine core substituted with thiophene, trifluoromethyl, cyano, and mercapto groups. This compound matters for its role as a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), particularly where the introduction of fluorine and sulfur-containing motifs is required for modulating biological activity or material properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with enhanced efficacy and stability.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies where the thienylpyridine scaffold is pharmacologically relevant.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene and pyridine rings.
• Material Science: Acts as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its conjugated system and electron-withdrawing groups.
• Ligand Synthesis: The mercapto and nitrogen donor sites make it a useful starting material for creating complexing agents and catalysts in coordination chemistry.
• Chemical Biology Probes: Employed in the design of molecular probes and tags for studying biological processes, benefiting from the specificity introduced by the trifluoromethyl group.

Basic Information

Product Name	2-Mercapto-6-Thien-2-Yl-4-(Trifluoromethyl)-Pyridine-3-Carbonitrile
CAS No.	104960-50-1
Molecular Formula	C12H5F3N2S2
Molecular Weight	298.31 g/mol
Synonyms	2-Mercapto-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile; 6-(Thiophen-2-yl)-2-sulfanyl-4-(trifluoromethyl)pyridine-3-carbonitrile; 2-Thien-2-yl-6-mercapto-4-trifluoromethyl-nicotinonitrile; 2-Mercapto-6-(2-thienyl)-4-(trifluoromethyl)-3-pyridinecarbonitrile; 104960-50-1; 2-Thienyl-6-mercapto-4-trifluoromethylnicotinonitrile; 3-Cyano-2-mercapto-6-(2-thienyl)-4-(trifluoromethyl)pyridine
EINECS	Contact for details

Quality Control

Our 2-Mercapto-6-Thien-2-Yl-4-(Trifluoromethyl)-Pyridine-3-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.