Description

(R)-2-Amino-3-(3-Fluorophenyl)Propionic Acid Ethyl Ester is a high-purity chiral building block essential for advanced pharmaceutical synthesis. Its value lies in its role as a key intermediate for introducing a fluorinated phenylalanine moiety with defined stereochemistry into target molecules. This compound is primarily needed by research institutions and pharmaceutical companies developing novel active pharmaceutical ingredients (APIs), particularly in the areas of neurology and metabolic disorders.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel fluorinated drug candidates.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate fluorinated amino acid analogs.
• Proteomics Research: Serves as a building block for creating specialized probes and inhibitors for enzyme studies.
• Asymmetric Synthesis: Employed in catalytic asymmetric reactions to construct complex molecules with high enantiomeric purity.
• Chemical Biology: Utilized in the design and synthesis of activity-based probes and molecular tools.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(R)-2-Amino-3-(3-Fluorophenyl)Propionic Acid Ethyl Ester
CAS No.	104880-96-8
Molecular Formula	C11H14FNO2
Molecular Weight	211.23 g/mol
Synonyms	(R)-3-(3-Fluorophenyl)alanine ethyl ester; Ethyl (R)-2-amino-3-(3-fluorophenyl)propanoate; (R)-3-Fluoro-DL-phenylalanine ethyl ester; D-3-(3-Fluorophenyl)alanine ethyl ester; (R)-3-Fluorophenylalanine ethyl ester; F-DL-Phe-OEt (R-enantiomer); (R)-α-Amino-3-fluoro-benzenepropanoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our (R)-2-Amino-3-(3-Fluorophenyl)Propionic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard pharmacopeial identification tests, to ensure it meets the high-purity standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Incompatible with strong alkalis and fluorinating agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.