Description

2-(1-Piperazinyl)-3-Pyridinecarboxylic Acid Methyl Ester is a high-purity, heterocyclic organic compound that serves as a critical building block in advanced chemical synthesis. This versatile intermediate is essential for research and development in the pharmaceutical sector, enabling the creation of novel active pharmaceutical ingredients (APIs). It is primarily sought by R&D chemists and process development scientists working in medicinal chemistry and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Fine Chemical Synthesis: Serves as a versatile building block for constructing more complex piperazine- and pyridine-containing molecules.
• API Development: Employed in the process research and scale-up stages for developing new active pharmaceutical ingredients.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for methodological development and bioorganic chemistry studies.

Basic Information

Product Name	2-(1-Piperazinyl)-3-Pyridinecarboxylic Acid Methyl Ester
CAS No.	104813-92-5
Molecular Formula	C11H15N3O2
Molecular Weight	221.26 g/mol
Synonyms	Methyl 2-(piperazin-1-yl)nicotinate; 3-Pyridinecarboxylic acid, 2-(1-piperazinyl)-, methyl ester; Methyl 2-piperazin-1-ylpyridine-3-carboxylate; 2-Piperazin-1-yl-nicotinic acid methyl ester; 104813-92-5; Methyl 2-(1-piperazinyl)nicotinate
EINECS	Contact for details

Quality Control

Our 2-(1-Piperazinyl)-3-Pyridinecarboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.