Description

Ethyl 3-Exo-Aminobicyclo[2.2.1]Hept-5-Ene-2-Exo-Carboxylate Hydrochloride is a high-purity, pharmaceutically relevant chiral building block and synthetic intermediate. This compound is valued for its rigid, functionalized bicyclic structure, which is crucial for imparting specific stereochemistry and biological activity in advanced drug molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly in medicinal chemistry and process research.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and antiviral drugs.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in drug discovery programs targeting specific biological receptors.
• Asymmetric Synthesis: Used as a precursor or auxiliary in catalytic asymmetric reactions to introduce stereogenic centers with high enantiomeric purity.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic routes for candidate drugs during clinical development phases.
• Academic Research: Utilized in universities and research institutes for studying reaction mechanisms, novel synthetic methodologies, and structure-activity relationships (SAR).

Basic Information

Item	Detail
Product Name	Ethyl 3-Exo-Aminobicyclo[2.2.1]Hept-5-Ene-2-Exo-Carboxylate Hydrochloride
CAS No.	104770-18-5
Molecular Formula	C11H18ClNO2
Molecular Weight	231.72 g/mol
Synonyms	Ethyl 3-exo-Aminobicyclo[2.2.1]hept-5-ene-2-exo-carboxylate HCl; 2-Norbornene-2-exo-carboxylic acid, 3-exo-amino-, ethyl ester, hydrochloride; Ethyl 3-Amino-5-norbornene-2-carboxylate Hydrochloride (exo,exo isomer); Bicyclo[2.2.1]hept-5-ene-2-exo-carboxylic acid, 3-exo-amino-, ethyl ester, hydrochloride; 3-exo-Amino-5-norbornene-2-exo-carboxylic acid ethyl ester hydrochloride; (1R,2S,3S,4R)-3-Amino-bicyclo[2.2.1]hept-5-ene-2-carboxylic acid ethyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our Ethyl 3-Exo-Aminobicyclo[2.2.1]Hept-5-Ene-2-Exo-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral analysis, to ensure high chemical and enantiomeric purity suitable for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.