Description

2-Pyrrolidinemethanol, 4-Hydroxy-, Hydrochloride (1:1), (2S,4R)- is a high-purity, stereochemically defined chiral building block of significant importance in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of pharmaceutical actives, particularly in the synthesis of complex molecules with specific biological activities. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the production of novel therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of protease inhibitors, neurological agents, and other bioactive molecules.
• Asymmetric Catalysis: Used as a precursor or ligand in the development of chiral catalysts for stereoselective reactions.
• Agrochemical Research: Serves as a building block for creating novel, enantiomerically pure pesticides and herbicides.
• Peptidomimetics: Incorporated into the backbone of peptide analogs to enhance metabolic stability and bioavailability.
• Academic & R&D: Employed in medicinal chemistry research for structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	2-Pyrrolidinemethanol, 4-Hydroxy-, Hydrochloride (1:1), (2S,4R)-
CAS No.	104587-51-1
Molecular Formula	C5H12ClNO2
Molecular Weight	153.61 g/mol
Synonyms	(2S,4R)-4-Hydroxy-2-pyrrolidinemethanol hydrochloride; (2S,4R)-4-Hydroxypyrrolidine-2-methanol hydrochloride; (4R)-4-Hydroxy-L-prolinol hydrochloride; L-Hydroxyprolinol hydrochloride; cis-4-Hydroxy-D-prolinol hydrochloride; (2S,4R)-2-(Hydroxymethyl)-4-hydroxypyrrolidine hydrochloride; 4-Hydroxy-L-prolinol HCl; (2S,4R)-1,2,4-Butanetriol, 1-amino-, hydrochloride (derivative)
EINECS	Contact for details

Quality Control

Our 2-Pyrrolidinemethanol, 4-Hydroxy-, Hydrochloride (1:1), (2S,4R)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with stringent specifications for pharmaceutical R&D and cGMP starting material applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and product integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (2S,4R)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.