Description

Norcarnitine tert-Butyl Ester is a high-purity, protected intermediate of significant importance in advanced organic synthesis. This compound is valued for its role as a key building block in the preparation of carnitine derivatives and other complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of metabolic modulators and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of L-carnitine and its analogs, which are investigated for their roles in fatty acid metabolism and energy production.
• Biochemical Research: Used as a protected form of norcarnitine in metabolic pathway studies and enzyme-substrate interaction research.
• Peptide & Prodrug Synthesis: Serves as a building block for introducing the carnitine moiety into peptides or for creating prodrugs with enhanced bioavailability.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes to study transporter proteins and metabolic disorders.

Basic Information

Product Name	Norcarnitine tert-Butyl Ester
CAS No.	104572-14-7
Molecular Formula	C9H19NO3
Molecular Weight	189.25 g/mol
Synonyms	3-Carboxy-N,N,N-trimethyl-2-propanaminium tert-butyl ester inner salt; (3-Carboxy-2-hydroxypropyl)trimethylammonium tert-butyl ester hydroxide inner salt; DL-Norcarnitine tert-butyl ester; tert-Butyl 3-carboxy-2-hydroxypropyl(trimethyl)azaniumylate; Norcarnitine t-butyl ester; 2-Hydroxy-3-trimethylammoniopropionate tert-butyl ester
EINECS	Contact for details

Quality Control

Our Norcarnitine tert-Butyl Ester is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture, to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.