Description

(S)-Pyrrolidin-2-Yl-Acetic Acid tert-Butyl Ester CAS NO 104553-43-7 is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound is valued for its role as a key building block in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of various drug candidates, particularly those targeting the central nervous system.
• API Development: Used in the research and production of Active Pharmaceutical Ingredients (APIs) requiring a pyrrolidine-based chiral scaffold.
• Agrochemical Synthesis: Serves as a building block for creating novel pesticides and herbicides with specific stereochemical requirements.
• Catalyst Ligand Precursor: Employed in the preparation of chiral ligands for asymmetric catalysis.
• Peptidomimetics Research: Utilized in medicinal chemistry for the design and synthesis of peptide-like molecules.
• Fine Chemical Production: Acts as a specialized intermediate in the manufacture of high-value, complex organic molecules.

Basic Information

Item	Details
Product Name	(S)-Pyrrolidin-2-Yl-Acetic Acid tert-Butyl Ester
CAS No.	104553-43-7
Molecular Formula	C10H19NO2
Molecular Weight	185.26 g/mol
Synonyms	(S)-2-(tert-Butoxycarbonylmethyl)pyrrolidine; (S)-1-Boc-2-pyrrolidineacetic acid; (S)-tert-Butyl 2-(pyrrolidin-2-yl)acetate; (S)-N-Boc-2-pyrrolidineacetic acid; (S)-2-Pyrrolidineacetic acid, 1-(1,1-dimethylethyl) ester; (S)-α-(1-Boc-2-pyrrolidinyl)acetic acid tert-butyl ester; (S)-1-(tert-Butoxycarbonyl)-2-pyrrolidineacetic acid
EINECS	Contact for details

Quality Control

Our (S)-Pyrrolidin-2-Yl-Acetic Acid tert-Butyl Ester is manufactured under strict quality control protocols to ensure high chemical and chiral purity suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, enantiomeric excess, and impurity profiles. Our quality systems support compliance with cGMP standards where required for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is sensitive to strong acids and organic solvents; keep away from incompatible materials. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.