Description

1-Trimethylsilyloxy-1-(3-Pyridyl)-Ethene is a specialized organosilicon reagent featuring a reactive enol ether moiety adjacent to a pyridine ring. This compound is a valuable synthetic building block, primarily used as a nucleophile in the formation of carbon-carbon bonds under mild conditions. It is essential for researchers and process chemists in the pharmaceutical and agrochemical industries engaged in the development of complex heterocyclic molecules. The compound is supplied with a high level of purity to ensure consistent and reliable reaction outcomes.

Application

• Pharmaceutical Intermediates: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) containing pyridine or dihydropyridine scaffolds.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require specific heterocyclic structures.
• Material Science Research: Serves as a monomer or functionalization agent in the development of novel organic electronic materials and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: Acts as a nucleophilic partner in palladium-catalyzed cross-coupling reactions, such as the Heck or Stille-type processes.
• Asymmetric Synthesis: Employed in enantioselective reactions to construct chiral centers adjacent to nitrogen-containing heterocycles.
• Chemical Biology Probes: Useful for the synthesis of labeled compounds or molecular probes for biological target identification and validation.

Basic Information

Product Name	1-Trimethylsilyloxy-1-(3-Pyridyl)-Ethene
CAS No.	104501-58-8
Molecular Formula	C10H15NOSi
Molecular Weight	193.32 g/mol
Synonyms	1-(Trimethylsilyloxy)-1-(3-pyridinyl)ethene; 1-(3-Pyridinyl)-1-[(trimethylsilyl)oxy]ethene; 1-(Pyridin-3-yl)-1-[(trimethylsilyl)oxy]ethene; 3-(1-Trimethylsilyloxyvinyl)pyridine; 1-Trimethylsiloxy-1-(3-pyridyl)ethylene; TMS enol ether of 3-acetylpyridine; 3-Acetylpyridine TMS enol ether
EINECS	Contact for details

Quality Control

Our 1-Trimethylsilyloxy-1-(3-Pyridyl)-Ethene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.