Description

Diethyl (((3-(2,6-Dimethyl-4-Pyridinyl)-4-Fluorophenyl)Amino)Methylene )Propanedioate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular architecture. Chemical manufacturers and R&D organizations in the global pharmaceutical and agrochemical sectors need this material to develop next-generation compounds with targeted biological activity.

Application

• Key synthetic intermediate in the research and development of new pharmaceutical candidates.
• Building block for the synthesis of complex molecules with potential kinase inhibitory activity.
• Precursor in agrochemical research for creating novel crop protection agents.
• Critical reagent in medicinal chemistry for structure-activity relationship (SAR) studies.
• Used in the development of fluorinated heterocyclic compounds for various life science applications.
• Intermediate in custom synthesis and contract manufacturing for specialized chemical entities.

Basic Information

Product Name	Diethyl (((3-(2,6-Dimethyl-4-Pyridinyl)-4-Fluorophenyl)Amino)Methylene )Propanedioate
CAS No.	104431-74-5
Molecular Formula	C21H23FN2O4
Molecular Weight	386.42 g/mol
Synonyms	Propanedioic acid, [[[3-(2,6-dimethyl-4-pyridinyl)-4-fluorophenyl]amino]methylene]-, diethyl ester; Diethyl (2Z)-2-[[3-(2,6-dimethylpyridin-4-yl)-4-fluorophenyl]amino-methylidene]propanedioate; (Z)-Diethyl 2-(((3-(2,6-dimethylpyridin-4-yl)-4-fluorophenyl)amino)methylene)malonate; CAS 104431-74-5; Malonic acid, [[[3-(2,6-dimethyl-4-pyridinyl)-4-fluorophenyl]amino]methylene]-, diethyl ester; Fluorinated pyridine malonate derivative
EINECS	Contact for details

Quality Control

Our Diethyl (((3-(2,6-Dimethyl-4-Pyridinyl)-4-Fluorophenyl)Amino)Methylene )Propanedioate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.