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(2R,3R)-2,3-o-(1-Phenylethylidene)-L-Tartaric Acid Dimethyl Ester CAS NO 104333-83-7


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CAS No.:104333-83-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(2R,3R)-2,3-o-(1-Phenylethylidene)-L-Tartaric Acid Dimethyl Ester is a high-purity chiral auxiliary and resolving agent derived from L-tartaric acid. This compound is critically important for its role in asymmetric synthesis, enabling the separation of enantiomers and the production of single-isomer pharmaceutical intermediates. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing and scaling up optically active compounds.

Application

  • Chiral Resolution Agent: For the separation of racemic mixtures of amines, amino acids, and other pharmaceutically relevant compounds.
  • Asymmetric Synthesis Catalyst/ Ligand Precursor: Used in the preparation of catalysts for enantioselective reactions, including dihydroxylations and epoxidations.
  • Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
  • Research & Development: A valuable tool in academic and industrial R&D for method development in stereochemistry and organic synthesis.
  • Fine Chemical Synthesis: Employed in the production of specialty chemicals, flavors, and fragrances where optical purity is essential.

Basic Information

Item Details
Product Name (2R,3R)-2,3-o-(1-Phenylethylidene)-L-Tartaric Acid Dimethyl Ester
CAS No. 104333-83-7
Molecular Formula C14H16O6
Molecular Weight 280.27 g/mol
Synonyms (2R,3R)-(-)-2,3-Di-O-(1-phenylethylidene)-L-threitol Dimethyl Ether; (2R,3R)-2,3-Di-O-(1-Phenylethylidene)-L-Tartaric Acid Dimethyl Ester; L-Tartaric Acid 2,3-(1-Phenylethylidene) Dimethyl Ester; (R,R)-(-)-2,3-Di-O-(α-methylbenzylidene)-L-threitol Dimethyl Ether; Dimethyl (2R,3R)-2,3-O-[(1S)-1-phenylethylidene]-L-tartrate; (2R,3R)-DIPT; (-)-DIPT
EINECS Contact for details

Quality Control

Our (2R,3R)-2,3-o-(1-Phenylethylidene)-L-Tartaric Acid Dimethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high enantiomeric purity and chemical identity. Certificates of Analysis (COA) detailing purity, specific rotation, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is light-sensitive (store away from light). Keep away from heat sources and incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Enantiomeric Purity (Chiral HPLC) ≥ 99.0% ee
Specific Rotation [α] Contact for details
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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