Description

(Z)-Ethyl-4,5-o-Isopropylidene-(R)-4,5-Dihydroxy-2-Pentenoate is a high-value chiral intermediate characterized by its protected diol functionality and specific stereochemistry. This compound is critical for ensuring enantiomeric purity in complex synthetic pathways, offering researchers and manufacturers a reliable building block for advanced chemical synthesis. It is primarily utilized in the pharmaceutical and fine chemical industries for the development of active pharmaceutical ingredients (APIs) and other specialty organic molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the asymmetric synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Used as a versatile building block for constructing natural products, agrochemicals, and other high-value specialty chemicals.
• Asymmetric Catalysis Research: Acts as a precursor or ligand in the development and study of new catalytic systems for stereoselective reactions.
• Academic & R&D Laboratories: Employed in research settings for methodological development and the exploration of new synthetic routes requiring protected diol units.

Basic Information

Product Name	(Z)-Ethyl-4,5-o-Isopropylidene-(R)-4,5-Dihydroxy-2-Pentenoate
CAS No.	104321-63-3
Molecular Formula	C11H18O5
Molecular Weight	230.26 g/mol
Synonyms	(Z)-Ethyl (R)-4,5-O-Isopropylidene-4,5-dihydroxy-2-pentenoate; (R)-4,5-O-Isopropylidene-4,5-dihydroxy-2-pentenoic Acid Ethyl Ester (Z-isomer); Ethyl (Z)-4,5-O-Isopropylidene-(R)-4,5-dihydroxy-2-pentenoate; (R)-Ethyl 4,5-O-Isopropylidene-4,5-dihydroxy-2-pentenoate (Z-form); Acetonide-protected (R)-pentenoate derivative
EINECS	Contact for details

Quality Control

Our (Z)-Ethyl-4,5-o-Isopropylidene-(R)-4,5-Dihydroxy-2-Pentenoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee (R-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.