Description

Ethyl (R)-(-)-3-(2,2-Dimethyl-1,3-Dioxolan-4-Yl)-trans-2-Propenoate is a high-value chiral intermediate, a protected form of (R)-(-)-3,4-Dihydroxybut-2-enoic acid ethyl ester, characterized by its stereochemical purity and functional group versatility. This compound is critical for the synthesis of complex bioactive molecules where precise stereochemistry is paramount for efficacy. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of chiral drugs, fine chemicals, and advanced material science applications.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, cardiovascular, and neurological drug candidates.
• Asymmetric Synthesis: Used as a precursor in stereoselective reactions to construct complex molecular architectures with defined chirality.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & Industrial Research: Serves as a valuable reagent in medicinal chemistry research and process development for novel therapeutic agents.
• Agrochemical Synthesis: Potential intermediate in the development of chiral pesticides and herbicides.

Basic Information

Item	Details
Product Name	Ethyl (R)-(-)-3-(2,2-Dimethyl-1,3-Dioxolan-4-Yl)-trans-2-Propenoate
CAS No.	104321-62-2
Molecular Formula	C10H16O4
Molecular Weight	200.23 g/mol
Synonyms	(R)-(-)-Ethyl 3-(2,2-Dimethyl-1,3-dioxolan-4-yl)-trans-acrylate; (R)-(-)-Ethyl 3-(2,2-Dimethyl-1,3-dioxolan-4-yl)-2-propenoate; (R)-(-)-3-(2,2-Dimethyl-1,3-dioxolan-4-yl)-trans-2-Propenoic Acid Ethyl Ester; (R)-(-)-Ethyl 3-(2,2-Dimethyl-1,3-dioxolan-4-yl)acrylate; (R)-(-)-Ethyl 3,4-O-Isopropylidene-2,3-dihydroxy-2-butenoate; (R)-(-)-Ethyl 3,4-O-Isopropylidenedihydroxybut-2-enoate; (R)-(-)-Dihydroxybutenoic Acid Ethyl Ester Acetonide
EINECS	Contact for details

Quality Control

Our production of Ethyl (R)-(-)-3-(2,2-Dimethyl-1,3-Dioxolan-4-Yl)-trans-2-Propenoate adheres to stringent quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is analyzed using advanced chromatographic (HPLC, GC) and spectroscopic (NMR, IR) techniques. Certificates of Analysis (COA) detailing purity, enantiomeric excess (ee), and impurity profiles are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be sensitive to moisture and prolonged exposure to air; keep container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.