Description

n-((5-Bromopyridin-3-Yl)Methyl)Propan-2-Amine is a high-purity brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its versatile reactivity, particularly as a key intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists working in medicinal chemistry, where it is used to introduce specific bromine-substituted pyridine motifs into target structures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized to develop molecular probes for studying enzyme function and protein interactions.
• Custom Synthesis and Contract Manufacturing: A key raw material for custom synthesis organizations (CSOs) producing bespoke compounds for client projects.

Basic Information

Product Name	n-((5-Bromopyridin-3-Yl)Methyl)Propan-2-Amine
CAS No.	104290-49-5
Molecular Formula	C9H13BrN2
Molecular Weight	229.12 g/mol
Synonyms	1-(5-Bromo-3-pyridinyl)-N-isopropylmethanamine; 1-(5-Bromopyridin-3-yl)-N-propan-2-ylmethanamine; 5-Bromo-3-[(isopropylamino)methyl]pyridine; N-[(5-Bromopyridin-3-yl)methyl]propan-2-amine; Isopropyl-(5-bromo-3-pyridylmethyl)amine; (5-Bromo-3-pyridylmethyl)isopropylamine; 3-[(Isopropylamino)methyl]-5-bromopyridine
EINECS	Contact for details

Quality Control

Our n-((5-Bromopyridin-3-Yl)Methyl)Propan-2-Amine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.