Description

(S)2,3-Dihydro-Indole-1,2-Dicarboxylic Acid 1-Benzyl Ester is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a key building block for constructing complex molecules with defined stereochemistry, which is critical for biological activity. This compound is essential for research and development laboratories and production facilities in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Asymmetric Synthesis: Used as a starting material or auxiliary in catalytic asymmetric reactions to produce enantiomerically pure compounds.
• Agrochemical Development: Serves as a building block for creating chiral active ingredients in herbicides, fungicides, and insecticides.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and the discovery of new chemical entities.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals requiring high stereochemical fidelity.
• Process Chemistry & Scale-up: Used in optimizing synthetic routes from milligram to kilogram scale for commercial production.

Basic Information

Product Name	(S)2,3-Dihydro-Indole-1,2-Dicarboxylic Acid 1-Benzyl Ester
CAS No.	104261-79-2
Molecular Formula	C18H15NO4
Molecular Weight	309.32 g/mol
Synonyms	(S)-1-Benzyl 1H-indole-1,2(3H)-dicarboxylate; (S)-1-Benzyl Indoline-1,2-dicarboxylate; (S)-1-Benzyl 2,3-dihydro-1H-indole-1,2-dicarboxylate; (S)-N-Benzyloxycarbonyl-2-carboxyindoline; (S)-1-(Benzyloxycarbonyl)indoline-2-carboxylic Acid; (S)-Cbz-2-COOH-Indoline; (S)-Indoline-1,2-dicarboxylic Acid 1-Benzyl Ester
EINECS	Contact for details

Quality Control

Our (S)2,3-Dihydro-Indole-1,2-Dicarboxylic Acid 1-Benzyl Ester is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.