Description

Decanedioic Acid, Bis(tert-Butyldimethylsilyl) Ester is a high-purity, protected derivative of sebacic acid, designed for advanced synthetic applications. This compound serves as a crucial protected intermediate, offering enhanced stability and selectivity in sensitive chemical transformations. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and specialty polymers.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide & Polymer Chemistry: Used as a protected monomer or linker for the controlled synthesis of specialty polyamides, polyesters, and peptide analogs.
• Organic Synthesis Reagent: Acts as a stable, silyl-protected diacid equivalent in reactions requiring selective functional group manipulation under basic or nucleophilic conditions.
• Material Science Research: Employed in the development of novel polymeric materials with tailored thermal and mechanical properties.
• Cross-coupling Reactions: Serves as a substrate in metal-catalyzed coupling reactions for constructing elongated molecular architectures.

Basic Information

Item	Details
Product Name	Decanedioic Acid, Bis(tert-Butyldimethylsilyl) Ester
CAS No.	104255-98-3
Molecular Formula	C22H46O4Si2
Molecular Weight	430.78 g/mol
Synonyms	Sebacic Acid Bis(TBDMS) Ester; Bis(tert-butyldimethylsilyl) Sebacate; 1,10-Bis[(tert-butyldimethylsilyl)oxy]-1,10-dioxodecane; Decanedioic Acid Bis(tert-butyldimethylsilyl) Ester; TBDMS Sebacate Ester; Di-TBDMS Sebacate; tert-Butyldimethylsilyl Sebacate
EINECS	Contact for details

Quality Control

Our Decanedioic Acid, Bis(tert-Butyldimethylsilyl) Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and traceability for your research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.