Description

Nonanedioic Acid, Bis(tert-Butyldimethylsilyl) Ester is a high-purity, protected derivative of azelaic acid, designed for advanced synthetic chemistry applications. This compound serves as a crucial, moisture-protected building block, enabling precise and efficient multi-step synthesis in sensitive reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials sectors for the synthesis of complex organic molecules.

Application

• Pharmaceutical Intermediate: Key protected synthon for the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates, particularly where carboxylic acid functionality needs temporary protection.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and plant growth regulators requiring specific dicarboxylic acid frameworks.
• Polymer & Material Science: Acts as a monomer or chain extender in the development of specialty polyesters, polyamides, and other performance polymers with tailored properties.
• Organic Synthesis & Catalysis: Employed in academic and industrial R&D for constructing complex natural products, macrocycles, and ligands for catalytic systems.
• Peptide & Protein Chemistry: Useful for introducing spacer arms or modifying biomolecules while protecting reactive carboxyl groups during synthesis.
• Flavor & Fragrance Industry: Intermediate for the synthesis of specific musk compounds and other fragrance ingredients with long-chain diacid backbones.

Basic Information

Product Name	Nonanedioic Acid, Bis(tert-Butyldimethylsilyl) Ester
CAS No.	104255-97-2
Molecular Formula	C21H46O4Si2
Molecular Weight	418.77 g/mol
Synonyms	Azelaic Acid Bis(TBDMS) Ester; Bis(tert-butyldimethylsilyl) Azelate; 1,9-Bis(tert-butyldimethylsilyloxy)-1,9-dioxononane; Nonanedioic Acid Bis(TBDMS) Ester; TBDMS Azelate; Di-TBDMS Azelate; tert-Butyldimethylsilyl Azelate; Azelaic Acid Di-TBDMS Ester
EINECS	Contact for details

Quality Control

Our Nonanedioic Acid, Bis(tert-Butyldimethylsilyl) Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.