Description

4-(4-(Bis(2-Chloroethyl)Amino)Phenyl)-1-Hydroxybutane-1,1-Bisphosphonic Acid is a nitrogen-containing bisphosphonate compound of significant interest in pharmaceutical research and development. This molecule matters for its potential as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of targeted therapeutic agents. It is primarily needed by R&D laboratories and pharmaceutical manufacturers focused on developing treatments for bone metabolism disorders and other specialized medical applications.

Application

• Key intermediate in the synthesis of novel nitrogen-containing bisphosphonate drug candidates.
• Research and development of potential osteoporosis and Paget's disease therapeutics.
• Precursor for compounds targeting bone metastasis associated with certain cancers.
• Building block for radiopharmaceutical chelating agents in diagnostic imaging.
• Reference standard for analytical method development and quality control in pharmaceutical manufacturing.
• Investigational material for studying bone mineral density regulation mechanisms.

Basic Information

Product Name	4-(4-(Bis(2-Chloroethyl)Amino)Phenyl)-1-Hydroxybutane-1,1-Bisphosphonic Acid
CAS No.	104233-81-0
Molecular Formula	C14H23Cl2NO7P2
Molecular Weight	450.18 g/mol
Synonyms	1-Hydroxy-4-[4-[bis(2-chloroethyl)amino]phenyl]butane-1,1-diphosphonic Acid; Norcantharidin Bisphosphonate Derivative; 4-(4-(Bis(2-chloroethyl)amino)phenyl)-1-hydroxy-1,1-butanediyldiphosphonic Acid; Phenylalanine Nitrogen Mustard Bisphosphonate Conjugate; N,N-Bis(2-chloroethyl)-4-aminophenyl Butane Bisphosphonate; Amino Bisphosphonate Chloroethyl Derivative; CAS 104233-81-0
EINECS	Contact for details

Quality Control

Our 4-(4-(Bis(2-Chloroethyl)Amino)Phenyl)-1-Hydroxybutane-1,1-Bisphosphonic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.