Description

1-tert-Butyl 4-Methyl (2S)-2-Aminobutanedioate is a high-purity, chiral protected amino acid derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a stereochemically defined scaffold for the construction of complex peptides and pharmaceutical intermediates. This compound is essential for research and development chemists in the pharmaceutical, biotechnology, and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used as a protected amino acid derivative in solid-phase and solution-phase peptide chemistry.
• Proteomics Research: Serves as a building block for creating custom peptides and peptide mimetics in biochemical research.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective chemical transformations.
• Chemical Biology: Utilized in the development of peptide-based probes, inhibitors, and diagnostic tools.
• Fine Chemical Production: Acts as a precursor for the manufacture of specialty chemicals and advanced materials.

Basic Information

Product Name	1-tert-Butyl 4-Methyl (2S)-2-Aminobutanedioate
CAS No.	104072-49-3
Molecular Formula	C9H17NO4
Molecular Weight	203.24 g/mol
Synonyms	(2S)-2-Amino-1-(tert-butoxy)-1-oxo-4-(methyloxy)butan-4-oate; 4-Methyl (2S)-2-[(tert-butoxycarbonyl)amino]butanedioate; L-Aspartic acid, 1-(1,1-dimethylethyl) 4-methyl ester; Boc-L-Asp(OMe)-OH; Boc-Asp(OMe)-OH; tert-Butyl hydrogen (2S)-2-amino-4-methoxy-4-oxobutanedioate; 1-tert-Butyl 4-methyl L-aspartate; N-Boc-L-aspartic acid 4-methyl ester
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl 4-Methyl (2S)-2-Aminobutanedioate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-purity standards suitable for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use and storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.