Description

4-Azidophenacetylthiocarnitine is a specialized biochemical reagent featuring an azido functional group, designed for advanced research and development applications. This compound is valued for its utility as a click chemistry handle or a photoaffinity labeling probe, enabling precise molecular tagging and interaction studies. It is primarily sought by researchers and developers in the fields of pharmaceutical discovery, proteomics, and chemical biology for investigating metabolic pathways and protein functions.

Application

• Click Chemistry Reagent: Used in bioorthogonal conjugation reactions for labeling biomolecules such as proteins, lipids, and nucleic acids.
• Photoaffinity Labeling (PAL): Serves as a critical probe to capture transient or weak protein-ligand interactions for target identification and validation in drug discovery.
• Metabolic Pathway Analysis: Employed in studies to trace and analyze carnitine-associated metabolic processes and enzyme functions.
• Proteomics Research: Facilitates the identification and characterization of novel protein targets and binding sites.
• Bioconjugation & Tool Compound Synthesis: Acts as a key intermediate for synthesizing more complex chemical probes and diagnostic agents.
• Academic & Industrial R&D: Supports fundamental and applied research in biochemistry and medicinal chemistry within university labs and biotech/pharma companies.

Basic Information

Product Name	4-Azidophenacetylthiocarnitine
CAS No.	104061-09-8
Molecular Formula	C18H25N4O4S
Molecular Weight	393.48 g/mol
Synonyms	4-Azidophenacetyl-L-carnitine thioester; N-(4-Azidophenacetyl)-L-carnitine thioester; L-Carnitine, 3-[(4-azidophenyl)acetyl]thio-; Azido-Phenacetyl-Carnitine; 4-Azidophenacetylthio-L-carnitine; PAL Carnitine Probe; Clickable Carnitine Probe; Azido Carnitine Derivative
EINECS	Contact for details

Quality Control

Our 4-Azidophenacetylthiocarnitine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as purity, identity, and impurity profile. We adhere to relevant industry standards for fine chemicals and can provide material suitable for GMP-grade development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This compound is light-sensitive (store away from light) and should be handled under appropriate laboratory conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.