Description

Diethyl 2-[(4-Acetylanilino)Methylene]Malonate is a versatile and high-purity chemical intermediate, primarily valued for its role as a key building block in the synthesis of complex heterocyclic compounds. Its unique molecular structure, featuring both an acetylanilino and a malonate ester group, makes it an essential precursor for creating advanced pharmaceutical actives and specialty fine chemicals. This product is critical for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors seeking reliable, high-quality intermediates for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of quinoline and other nitrogen-containing heterocycles, which are core structures in numerous active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactivity to form complex molecular architectures.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and functional materials requiring specific chromophores or electronic properties.
• Research & Development: Employed in academic and industrial R&D labs for method development and the creation of new chemical entities for screening.
• Material Science: Potential use in the synthesis of organic semiconductors, ligands for catalysts, or monomers for specialized polymers.

Basic Information

Product Name	Diethyl 2-[(4-Acetylanilino)Methylene]Malonate
CAS No.	104007-11-6
Molecular Formula	C₁₆H₁₉NO₅
Molecular Weight	305.33 g/mol
Synonyms	Diethyl (4-acetamidobenzylidene)malonate; Diethyl 2-[(4-Acetamidobenzylidene)]malonate; 2-[(4-Acetylanilino)methylene]malonic Acid Diethyl Ester; Propanedioic acid, 2-[(4-acetylphenyl)amino]methylene]-, 1,3-diethyl ester; (4-Acetamidobenzylidene)malonic Acid Diethyl Ester; Diethyl (4-acetylaminobenzylidene)malonate; Ethyl (E)-3-((4-acetamidophenyl)amino)-2-cyanoacrylate precursor
EINECS	Contact for details

Quality Control

Our Diethyl 2-[(4-Acetylanilino)Methylene]Malonate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for sensitive synthesis applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The compound is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.