Description

(E)-4-Hydroxy-2-Methyl-2-Butenoic Acid [(3Ar)-2,3,3Aβ,4,5,6,6Aβ,7,9Aβ,9Bα-Decahydro-6α-Hydroxymethyl-9-Methyl-3-Methylene-2-Oxoazuleno[4,5-B]Furan-4α-Yl] Ester is a complex, high-purity chemical ester with a defined stereochemistry, serving as a critical advanced intermediate in sophisticated organic synthesis. Its value lies in its unique molecular architecture, which makes it an essential building block for constructing complex natural product analogs and bioactive molecules. This compound is primarily needed by research institutions and pharmaceutical development teams focused on medicinal chemistry, process R&D, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for complex target molecules.
• Medicinal Chemistry Research: Used as a sophisticated scaffold or precursor for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Natural Product Synthesis: Serves as a critical intermediate in the total or semi-synthesis of complex natural products and their derivatives for biological evaluation.
• Process Chemistry Development: Employed in route scouting and scale-up studies for the efficient production of high-value fine chemicals and candidate drugs.
• Biochemical Probe Development: Utilized in the creation of specialized molecular probes for studying enzyme mechanisms or biological pathways.
• Academic & Institutional Research: A valuable reagent for advanced organic synthesis projects in university and institutional laboratories.

Basic Information

Item	Details
Product Name	(E)-4-Hydroxy-2-Methyl-2-Butenoic Acid [(3Ar)-2,3,3Aβ,4,5,6,6Aβ,7,9Aβ,9Bα-Decahydro-6α-Hydroxymethyl-9-Methyl-3-Methylene-2-Oxoazuleno[4,5-B]Furan-4α-Yl] Ester
CAS No.	103974-70-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	4-Hydroxy-2-methyl-2-butenoic acid (3aR,4S,6aR,7R,9aS,9bR)-decahydro-6a-(hydroxymethyl)-9-methyl-3-methylene-2-oxoazuleno[4,5-b]furan-4-yl ester; (E)-4-Hydroxy-2-methyl-2-butenoic acid ester with a decahydroazulenofuran derivative; Azuleno[4,5-b]furan-4-ol, 2,3,3a,4,5,6,6a,7,9a,9b-decahydro-6a-(hydroxymethyl)-9-methyl-3-methylene-2-oxo-, 4-(3-methyl-2-butenoate), (3aR,4S,6aR,7R,9aS,9bR)-; CAS 103974-70-5.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high purity. All materials are characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing specifications and test results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This compound may be sensitive to moisture and oxidation; prolonged exposure to air or elevated temperatures should be avoided.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.