Description

1-(Chloromethyl)-3,5-Bis[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]Benzene CAS NO 103929-85-7 is a high-value, protected intermediate featuring chloromethyl and tert-butyldimethylsilyl (TBDMS) ether protecting groups. This compound is critical for advanced organic synthesis, offering chemists a versatile and stable building block for constructing complex molecular architectures. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries for the development of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Serves as a key protected synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring selective deprotection strategies.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides where the TBDMS group provides stability during synthesis.
• Organic Synthesis Building Block: Employed in academic and industrial research for constructing complex phenols, polyphenols, and other aromatic systems under controlled conditions.
• Material Science Precursor: Acts as a monomer or functionalization agent in the development of specialized polymers and advanced organic materials.
• Process Chemistry: Valued in scale-up and pilot plant operations for its defined reactivity and compatibility with various organic solvents and reagents.

Basic Information

Product Name	1-(Chloromethyl)-3,5-Bis[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]Benzene
CAS No.	103929-85-7
Molecular Formula	C19H35ClO2Si2
Molecular Weight	387.10 g/mol
Synonyms	3,5-Bis[(tert-butyldimethylsilyl)oxy]benzyl Chloride; 1-(Chloromethyl)-3,5-bis[(tert-butyldimethylsilyl)oxy]benzene; 3,5-Bis-O-(tert-butyldimethylsilyl)benzyl Chloride; Benzyl Chloride, 3,5-bis[(tert-butyldimethylsilyl)oxy]-; TBDMS-protected 3,5-Dihydroxybenzyl Chloride; 103929-85-7; 3,5-Di-O-TBDMS Benzyl Chloride
EINECS	Contact for details

Quality Control

Our production of 1-(Chloromethyl)-3,5-Bis[[(1,1-Dimethyl-ethyl)Dimethylsilyl]Oxy]Benzene adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All material is characterized by advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be kept under an inert atmosphere for long-term storage to maximize stability. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.