Description

3,5-Bis[[(tert-Butyl)Dimethylsilyl]Oxy]Benzenemethanol is a key organosilicon-protected intermediate, specifically designed for advanced organic synthesis where selective deprotection is required. Its primary value lies in providing robust protection for phenolic hydroxyl groups under a wide range of reaction conditions, enabling complex multi-step syntheses. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of complex drug molecules, particularly those requiring selective protection/deprotection strategies.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where phenolic group manipulation is necessary.
• Material Science Research: Serves as a precursor for novel polymers and dendrimers with specific functional group architectures.
• Ligand and Catalyst Development: Employed in the creation of sophisticated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic & R&D Laboratories: A valuable reagent for methodological development in synthetic organic chemistry.
• Fine Chemical Production: Enables the manufacture of high-value, low-volume specialty chemicals with precise structural features.

Basic Information

Product Name	3,5-Bis[[(tert-Butyl)Dimethylsilyl]Oxy]Benzenemethanol
CAS No.	103929-84-6
Molecular Formula	C19H34O3Si2
Molecular Weight	366.64 g/mol
Synonyms	3,5-Bis[(tert-butyldimethylsilyl)oxy]benzenemethanol; 1,3-Benzenedimethanol, 5-hydroxy-, 1,3-bis-O-(tert-butyldimethylsilyl) ether; 3,5-Bis-O-(tert-butyldimethylsilyl)benzyl alcohol; 3,5-Bis(TBDMS-oxy)benzyl alcohol; TBDMS-protected 3,5-dihydroxybenzyl alcohol; 3,5-Di-O-TBDMS benzyl alcohol
EINECS	Contact for details

Quality Control

Our 3,5-Bis[[(tert-Butyl)Dimethylsilyl]Oxy]Benzenemethanol is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for demanding synthetic applications. We provide comprehensive analytical data, including HPLC, NMR, and GC-MS, to verify identity and purity. Certificates of Analysis (COA) are available for every batch upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.