Description

3,5-Bis(tert-Butyldimethylsiloxyl)Benzoic Acid Methyl Ester is a high-value, protected benzoic acid derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in the dual tert-butyldimethylsilyl (TBDMS) protecting groups, which provide exceptional stability for sensitive functional group manipulations under demanding reaction conditions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where it is utilized in the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and specialty polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs), particularly where phenol protection is required.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Advanced Material Precursor: Serves as a monomer or intermediate in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Organic Synthesis Reagent: A versatile reagent in academic and industrial R&D for constructing aromatic systems with protected hydroxyl functionalities.
• Chemical Biology Probe Development: Employed in the synthesis of molecular probes and tags for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring precise, multi-step organic transformations.

Basic Information

Product Name	3,5-Bis(tert-Butyldimethylsiloxyl)Benzoic Acid Methyl Ester
CAS No.	103929-83-5
Molecular Formula	C21H38O4Si2
Molecular Weight	410.70 g/mol
Synonyms	Methyl 3,5-bis[(tert-butyldimethylsilyl)oxy]benzoate; Benzoic acid, 3,5-bis[(1,1-dimethylethyl)dimethylsilyl]oxy]-, methyl ester; 3,5-Bis-O-(tert-butyldimethylsilyl)methyl benzoate; Methyl 3,5-di-O-tert-butyldimethylsilylbenzoate; 3,5-Bis(TBDMS-oxy)methyl benzoate; TBDMS-protected methyl 3,5-dihydroxybenzoate; 3,5-Di-O-TBDMS methyl benzoate
EINECS	Contact for details

Quality Control

Our 3,5-Bis(tert-Butyldimethylsiloxyl)Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment. We support compliance with cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container must be kept tightly sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.