Description

Bromo-2,3,4-Tri-o-Benzoyl-α-D-Glucuronic Acid Methyl Ester is a key protected glycosyl donor and advanced synthetic intermediate in carbohydrate chemistry. This compound is essential for the controlled synthesis of complex oligosaccharides and glycoconjugates, where precise stereochemistry is critical. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, diagnostic agents, and biochemical tools.

Application

• Glycosylation Reactions: Serves as a crucial building block for the stereoselective synthesis of glucuronide derivatives and complex carbohydrate structures.
• Pharmaceutical Intermediate: Used in the research and development of prodrugs, targeted drug delivery systems, and metabolites for pharmacokinetic studies.
• Bioconjugate Chemistry: Facilitates the creation of antibody-drug conjugates (ADCs) and other targeted biomolecules by providing a functionalized sugar moiety.
• Chemical Biology Probes: Enables the synthesis of labeled sugars and activity-based probes for studying glycosyltransferases and other enzymes.
• Standards and Reference Materials: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Details
Product Name	Bromo-2,3,4-Tri-o-Benzoyl-α-D-Glucuronic Acid Methyl Ester
CAS No.	103674-69-7
Molecular Formula	C29H23BrO10
Molecular Weight	611.39 g/mol
Synonyms	Methyl (2,3,4-Tri-O-benzoyl-α-D-glucopyranosyl bromide)uronate; Methyl 2,3,4-Tri-O-benzoyl-α-D-glucopyranosyl bromide uronate; α-D-Glucopyranosyl bromide, methyl 2,3,4-tri-O-benzoyl-1-carboxylate; Glucuronic Acid Methyl Ester, Bromo-2,3,4-Tri-o-Benzoyl-α-D-; Tri-O-benzoyl-α-D-glucopyranosyl bromide methyl ester
EINECS	Contact for details

Quality Control

Our Bromo-2,3,4-Tri-o-Benzoyl-α-D-Glucuronic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the exacting standards required for synthetic and research applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed under inert atmosphere or with desiccant to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.