Description

n-(p-Azidobenzoyl)Daunorubicin is a chemically modified derivative of the anthracycline antibiotic daunorubicin, designed for advanced research applications. This compound is a critical tool for scientists developing targeted drug delivery systems and photochemical probes due to its photoreactive azido group. It is primarily utilized by researchers in pharmaceutical R&D, biochemistry, and oncology for studying drug mechanisms, antibody-drug conjugates (ADCs), and site-specific labeling.

Application

• Photochemical Crosslinking Studies: Used as a photoreactive probe to investigate biomolecular interactions and protein binding sites.
• Antibody-Drug Conjugate (ADC) Research: Serves as a key intermediate or model payload in the development of targeted cancer therapeutics.
• Mechanism of Action Analysis: Employed to study the cellular uptake, localization, and activity of anthracycline-based drugs.
• Bioconjugation and Labeling: Facilitates the covalent attachment of daunorubicin to antibodies, peptides, or other targeting molecules via its reactive azido moiety.
• Academic and Pharmaceutical R&D: A vital reagent for universities and biotech companies exploring novel chemotherapeutic strategies and drug delivery platforms.

Basic Information

Product Name	n-(p-Azidobenzoyl)Daunorubicin
CAS No.	103597-53-1
Molecular Formula	C35H33N5O11
Molecular Weight	699.67 g/mol
Synonyms	Daunorubicin 4-azidobenzoate; 4'-Azidobenzoyldaunorubicin; N-(4-Azidobenzoyl)daunorubicin; p-Azidobenzoyldaunorubicin; Daunorubicin-14-(4-azidobenzoate); 14-O-(4-Azidobenzoyl)daunorubicin; AD 143; AD-143
EINECS	Contact for details

Quality Control

Our n-(p-Azidobenzoyl)Daunorubicin is manufactured under strict quality protocols suitable for research use. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing batch-specific results is provided to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This compound is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	Red to orange-red solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.