Description

Dimethyl-(2,3-Dimethyl-2-Butyl)Silyl Trifluoromethanesulfonate is a highly reactive organosilicon reagent, specifically a silyl triflate, valued for its role as a powerful silylating agent and protecting group activator in sophisticated organic synthesis. Its primary commercial value lies in enabling the efficient and selective introduction of the bulky, sterically hindered dimethyl(2,3-dimethyl-2-butyl)silyl group, which is crucial for protecting sensitive functional groups during multi-step synthetic sequences. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors, where precise molecular construction is paramount.

Application

• Pharmaceutical Intermediate Synthesis: As a key reagent for the protection of alcohols, phenols, and carboxylic acids in the multi-step synthesis of active pharmaceutical ingredients (APIs).
• Agrochemical Production: Used in the construction of complex molecules for novel pesticides and herbicides, where selective protection/deprotection strategies are required.
• Advanced Material Research: Employed in the synthesis of specialized silicon-containing polymers, dendrimers, and liquid crystals for electronic and optical applications.
• Natural Product Synthesis: Facilitates the challenging synthesis of complex natural products by providing robust protection for hydroxyl groups under demanding reaction conditions.
• Process Chemistry & Scale-Up: Valued in pilot plant and manufacturing settings for its consistent reactivity and purity, enabling reliable scale-up of synthetic routes.
• Catalyst & Ligand Development: Used to synthesize novel organosilicon-based ligands and catalysts for asymmetric synthesis and polymerization processes.

Basic Information

Product Name	Dimethyl-(2,3-Dimethyl-2-Butyl)Silyl Trifluoromethanesulfonate
CAS No.	103588-79-0
Molecular Formula	C9H19F3O3SSi
Molecular Weight	292.39 g/mol
Synonyms	Dimethyl(2,3-dimethyl-2-butyl)silyl Triflate; (2,3-Dimethyl-2-butyl)dimethylsilyl Trifluoromethanesulfonate; t-Hexyldimethylsilyl Trifluoromethanesulfonate; t-Hexyldimethylsilyl Triflate; t-HexMe2SiOTf; (1,1,2-Trimethylpropyl)dimethylsilyl Triflate; Thexyldimethylsilyl Trifluoromethanesulfonate; Thexyldimethylsilyl Triflate
EINECS	Contact for details

Quality Control

Our Dimethyl-(2,3-Dimethyl-2-Butyl)Silyl Trifluoromethanesulfonate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high reactivity. Each lot undergoes rigorous analytical testing, including NMR, GC, and HPLC analysis, to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.