Description

Methyl 2-Iodo-5-Methylbenzoate is a high-purity iodinated aromatic ester building block of significant importance in advanced organic synthesis. Its core value proposition lies in providing a versatile and reactive site for cross-coupling reactions and further functionalization, enabling the construction of complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic motifs for biological activity or further derivatization.
• Agrochemical Synthesis: Used in research and development for creating new herbicides, fungicides, and insecticides where the iodine atom serves as a handle for introducing other functional groups.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and advanced polymers, where its structure can influence material properties.
• Cross-Coupling Reactions: Serves as an excellent substrate for palladium-catalyzed reactions such as Suzuki, Stille, and Sonogashira couplings to form new carbon-carbon bonds.
• Ligand and Catalyst Development: Utilized as a building block for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Acts as a starting material for creating tagged molecules or probes used in biochemical and diagnostic research.

Basic Information

Product Name	Methyl 2-Iodo-5-Methylbenzoate
CAS No.	103440-52-4
Molecular Formula	C9H9IO2
Molecular Weight	276.07 g/mol
Synonyms	2-Iodo-5-methylbenzoic acid methyl ester; Methyl 2-iodo-5-methylbenzoate; Methyl 2-iodo-p-toluate; Benzoic acid, 2-iodo-5-methyl-, methyl ester; 5-Methyl-2-iodobenzoic acid methyl ester; 2-Iodo-5-methyl methylbenzoate; Methyl 5-methyl-2-iodobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 2-Iodo-5-Methylbenzoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes rigorous analytical testing, including HPLC, GC, and NMR, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.