Description

3-Amino-5-Phenyl-1,3-Dihydro-2H-1,4-Benzodiazepin-2-One is a high-purity benzodiazepine derivative, a crucial advanced pharmaceutical intermediate for the synthesis of novel therapeutic agents. Its value lies in providing a reliable, structurally defined building block for research and development in medicinal chemistry. This compound is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new central nervous system (CNS) active compounds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel benzodiazepine-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a scaffold or building block in drug discovery programs targeting GABAA receptors.
• Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Utilized in studies investigating the structure-activity relationships (SAR) of benzodiazepine compounds.
• Process Development: Acts as a critical material for scaling up and optimizing synthetic routes in pilot plant studies.

Basic Information

Product Name	3-Amino-5-Phenyl-1,3-Dihydro-2H-1,4-Benzodiazepin-2-One
CAS No.	103343-47-1
Molecular Formula	C15H13N3O
Molecular Weight	251.28 g/mol
Synonyms	3-Amino-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 5-Phenyl-3-amino-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 3-Amino-5-phenyl-1H-1,4-benzodiazepin-2(3H)-one; 103343-47-1; 3-Amino-5-phenyl-2H-1,4-benzodiazepin-2-one; 5-Phenyl-3-amino-2H-1,4-benzodiazepin-2-one
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Phenyl-1,3-Dihydro-2H-1,4-Benzodiazepin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.