Description

Malonic Acid, Benzyl (2-Dimethylaminoethyl)-, Bis(Tetrahydropyran-2-Yl) Ester is a specialized, high-purity chemical intermediate designed for advanced synthesis. This compound is valued for its role as a protected malonate derivative, offering controlled reactivity in complex organic transformations. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of active pharmaceutical ingredients (APIs) and novel fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Organic Synthesis Reagent: Used in C-C bond-forming reactions, such as Michael additions and alkylations, where a protected malonate moiety is required.
• Peptidomimetics Research: Serves as a precursor for introducing specific functional groups into peptide analogs and bio-active compounds.
• Agrochemical Synthesis: Employed in the research and development of advanced pesticides and herbicides.
• Material Science Research: Used in the synthesis of specialty polymers and functional organic materials.
• Academic & R&D Laboratories: A valuable reagent for methodological development and exploratory chemistry in university and industrial research settings.

Basic Information

Product Name	Malonic Acid, Benzyl (2-Dimethylaminoethyl)-, Bis(Tetrahydropyran-2-Yl) Ester
CAS No.	102891-39-4
Molecular Formula	C24H35NO5
Molecular Weight	417.54 g/mol
Synonyms	Benzyl (2-Dimethylaminoethyl)malonate Bis(Tetrahydropyran-2-Yl) Ester; 2-(Benzyloxycarbonyl)-2-(2-(dimethylamino)ethyl)malonic Acid Bis(5,6-dihydro-2H-pyran-2-yl) Ester; 2-(Benzyloxycarbonyl)-2-[2-(dimethylamino)ethyl]propanedioic Acid Bis(3,4,5,6-tetrahydro-2H-pyran-2-yl) Ester; THP-Protected Malonate Ester; Malonic Acid Derivative CAS 102891-39-4
EINECS	Contact for details

Quality Control

Our production of Malonic Acid, Benzyl (2-Dimethylaminoethyl)-, Bis(Tetrahydropyran-2-Yl) Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.