Description

2-Azido-1-(1,3-Benzodioxol-5-yl)ethanone is a specialized organic building block featuring a reactive azido functional group attached to a benzodioxole ketone scaffold. This compound matters for its role as a versatile intermediate in click chemistry and bioorthogonal labeling applications, enabling the efficient synthesis of complex molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting neurological pathways.
• Click Chemistry Reagent: Utilized in Huisgen 1,3-dipolar cycloaddition reactions with alkynes to form stable triazole linkages, a cornerstone of modern bioconjugation.
• Bioconjugation & Probe Synthesis: Enables the labeling of biomolecules (proteins, antibodies, nucleic acids) with fluorescent dyes or other reporter groups for diagnostic and imaging applications.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides by providing a reactive handle for structural diversification.
• Polymer & Material Science: Acts as a functional monomer or cross-linking agent for creating advanced polymers with specific thermal or mechanical properties.
• Chemical Biology Studies: Employed to probe enzyme activity or cellular processes through its bioorthogonal reactivity profile.

Basic Information

Product Name	2-Azido-1-(1,3-Benzodioxol-5-yl)ethanone
CAS No.	102831-07-2
Molecular Formula	C9H7N3O3
Molecular Weight	205.17 g/mol
Synonyms	2-Azido-1-(benzo[d][1,3]dioxol-5-yl)ethan-1-one; 1-(1,3-Benzodioxol-5-yl)-2-azidoethanone; 2-Azido-1-(3,4-methylenedioxyphenyl)ethanone; 5-(2-Azidoacetyl)-1,3-benzodioxole; Azidomethyl 3,4-methylenedioxyphenyl ketone; 102831-07-2 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 2-Azido-1-(1,3-Benzodioxol-5-yl)ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to the presence of the azido group, which can be shock-sensitive, handle with appropriate care and avoid exposure to heat, strong light, or mechanical shock. Keep away from incompatible materials such as strong reducing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.