Description

Benzoic Acid, 4-[(1S)-1-Hydroxyethyl]-, Methyl Ester is a chiral, optically active ester derivative of benzoic acid, serving as a critical intermediate in advanced organic synthesis. Its defined stereochemistry and functional groups make it a valuable building block for constructing complex molecules with high enantiomeric purity. This compound is essential for research and production in the pharmaceutical and fine chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of enantiomerically pure drugs.
• Asymmetric Synthesis: Used as a starting material or auxiliary in catalytic asymmetric reactions to introduce stereogenic centers.
• Liquid Crystal & Advanced Material Precursor: Serves as a building block for creating chiral dopants and organic components in liquid crystal displays and specialty polymers.
• Agrochemical Synthesis: Employed in the research and development of chiral pesticides and herbicides for enhanced efficacy and selectivity.
• Flavor & Fragrance Chemistry: Acts as an intermediate for synthesizing specific, high-value aromatic esters used in premium fragrance compositions.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and process chemistry research.

Basic Information

Product Name	Benzoic Acid, 4-[(1S)-1-Hydroxyethyl]-, Methyl Ester
CAS No.	102681-71-0
Molecular Formula	C10H12O3
Molecular Weight	180.20 g/mol
Synonyms	(S)-Methyl 4-(1-Hydroxyethyl)benzoate; Methyl (S)-4-(1-Hydroxyethyl)benzoate; (S)-(-)-Methyl 4-(1-Hydroxyethyl)benzoate; p-[(1S)-1-Hydroxyethyl]benzoic Acid Methyl Ester; Benzoic acid, 4-[(1S)-1-hydroxyethyl]-, methyl ester; (S)-Methyl p-(1-hydroxyethyl)benzoate; (1S)-1-(4-Methoxycarbonylphenyl)ethanol
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 4-[(1S)-1-Hydroxyethyl]-, Methyl Ester is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. We provide comprehensive analytical data, including Chiral HPLC for enantiomeric excess (ee) determination and standard identity/purity tests. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Specific Rotation	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.