Description

Methyl 3-(1-Tritylimidazol-4-Yl) Propionate is a high-value, protected imidazole derivative primarily used as a sophisticated synthetic intermediate in advanced organic chemistry. Its core value lies in the trityl-protected imidazole nitrogen, which allows for selective functionalization in complex multi-step syntheses. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those containing imidazole or histidine-like moieties.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides where the imidazole ring is a critical pharmacophore.
• Peptidomimetics & Bioconjugation: Facilitates the creation of peptide analogs and bioconjugates by providing a protected handle for selective coupling reactions.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Academic & R&D Laboratories: Employed in methodological research and the discovery of new chemical entities (NCEs) in university and corporate settings.
• Custom Synthesis & Contract Manufacturing: A critical starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	Methyl 3-(1-Tritylimidazol-4-Yl) Propionate
CAS No.	102676-60-8
Molecular Formula	C27H26N2O2
Molecular Weight	410.51 g/mol
Synonyms	Methyl 3-(1-Triphenylmethyl-1H-imidazol-4-yl)propanoate; 1-Trityl-4-(2-methoxycarbonylethyl)imidazole; Methyl 3-(1-Trityl-1H-imidazol-4-yl)propionate; 1H-Imidazole-4-propanoic acid, 1-(triphenylmethyl)-, methyl ester; Methyl 1-tritylimidazole-4-propionate; Trityl-protected imidazole propionate ester
EINECS	Contact for details

Quality Control

Our Methyl 3-(1-Tritylimidazol-4-Yl) Propionate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.