Description

n-Succinimidyl-4-(2-Nitrovinyl)Benzoate is a specialized heterobifunctional crosslinking reagent featuring a photoreactive nitrovinyl group and an amine-reactive N-hydroxysuccinimide (NHS) ester. This compound matters for its ability to facilitate photoaffinity labeling and the covalent conjugation of biomolecules under mild, controlled conditions. It is primarily needed by researchers and manufacturers in bioconjugation, proteomics, and pharmaceutical development for creating stable, photo-activatable probes and conjugates.

Application

• Photoaffinity Labeling Probes: Used to create covalent bonds with target proteins or biomolecules upon UV light activation for studying molecular interactions.
• Bioconjugation & Immobilization: Acts as a crosslinker for attaching peptides, proteins, or other amine-containing ligands to surfaces, particles, or other molecules.
• Proteomics Research: Employed in the development of activity-based probes (ABPs) to identify and characterize enzymes and their active sites.
• Diagnostic Reagent Synthesis: A key intermediate in the production of reagents for immunoassays and biosensors.
• Drug Discovery: Utilized in the synthesis of targeted drug conjugates and for studying drug-target engagement.
• Materials Science: Facilitates the functionalization of polymers and nanomaterials with bioactive molecules.

Basic Information

Product Name	n-Succinimidyl-4-(2-Nitrovinyl)Benzoate
CAS No.	102564-38-5
Molecular Formula	C13H10N2O6
Molecular Weight	290.23 g/mol
Synonyms	4-(2-Nitrovinyl)benzoic acid N-succinimidyl ester; N-Succinimidyl 4-(2-nitrovinyl)benzoate; S-4-(2-Nitrovinyl)benzoate; NHS ester of 4-(2-Nitrovinyl)benzoic acid; 4-Nitrovinylbenzoic acid succinimidyl ester; SNVB; Photoactivatable NHS ester crosslinker
EINECS	Contact for details

Quality Control

Our n-Succinimidyl-4-(2-Nitrovinyl)Benzoate is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality management standards to guarantee reliable supply and product integrity for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant in a dry environment. Due to its hygroscopic and light-sensitive nature, allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake and decomposition.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Water Content (KF)	< 1.0%
Solubility	Soluble in DMSO, DMF, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.