Description

3-Fluorobenzyl Isocyanate is a versatile and reactive aromatic isocyanate building block essential for introducing the 3-fluorobenzyl moiety into complex molecular architectures. Its primary value lies in its role as a key intermediate for synthesizing pharmaceuticals, agrochemicals, and advanced materials, where it facilitates the formation of ureas, carbamates, and other functional groups. This compound is particularly critical for R&D and production chemists in the pharmaceutical and specialty chemical industries seeking to develop novel active ingredients and performance chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Polymer & Material Science: Serves as a monomer or cross-linking agent in the synthesis of specialty polyurethanes, coatings, and adhesives with tailored properties.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A fundamental building block in medicinal chemistry and organic synthesis for constructing urea and carbamate derivatives.
• Dye & Pigment Manufacturing: Used in the synthesis of specialized colorants and functional dyes.

Basic Information

Product Name	3-Fluorobenzyl Isocyanate
CAS No.	102422-56-0
Molecular Formula	C8H6FNO
Molecular Weight	151.14 g/mol
Synonyms	1-Isocyanatomethyl-3-fluorobenzene; (3-Fluorophenyl)methyl isocyanate; m-Fluorobenzyl isocyanate; 3-Fluorobenzylisocyanate; α-Isocyanato-3-fluorotoluene; 3-Fluorobenzyl carbimide; 3-Fluoro-α-isocyanatotoluene
EINECS	Contact for details

Quality Control

Our 3-Fluorobenzyl Isocyanate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, open flames, and incompatible materials such as water, alcohols, amines, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.