Description

4-Trifluoromethylbenzylisocyanate is a versatile and reactive aromatic isocyanate building block, essential for synthesizing advanced chemical intermediates. Its value lies in the unique combination of the isocyanate group's reactivity and the electron-withdrawing, lipophilic trifluoromethyl substituent, which can significantly alter the properties of final compounds. This compound is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring the trifluoromethyl group for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often contributes to improved efficacy and environmental profile.
• Polymer & Material Science: Serves as a monomer or cross-linking agent in the development of specialty polyurethanes, coatings, and adhesives with tailored chemical resistance and surface properties.
• Chemical Research & Development: A critical reagent for medicinal chemistry and drug discovery programs, enabling the rapid exploration of structure-activity relationships (SAR).
• Liquid Crystal & Electronic Materials: Employed in the synthesis of components for display technologies and organic semiconductors, where specific molecular architecture is required.

Basic Information

Product Name	4-Trifluoromethylbenzylisocyanate
CAS No.	102422-55-9
Molecular Formula	C9H6F3NO
Molecular Weight	201.15 g/mol
Synonyms	α-Isocyanato-4-(trifluoromethyl)toluene; 1-Isocyanatomethyl-4-(trifluoromethyl)benzene; 4-(Trifluoromethyl)benzyl isocyanate; p-(Trifluoromethyl)benzyl isocyanate; (4-Trifluoromethylphenyl)methyl isocyanate; Benzene, 1-(isocyanatomethyl)-4-(trifluoromethyl)-; α-Isocyanato-α,α,α-trifluoro-p-xylene
EINECS	Contact for details

Quality Control

Our 4-Trifluoromethylbenzylisocyanate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation by atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.